So, there is nothing you need to find on your computer. The digital license is linked to your Microsoft account and associated with your hardware. Read More Activate Windows 11 via Digital License Have a Volume Licensing agreement for Win11 or MSDN subscription.Pay a digital copy of Windows 11 from an authorized retailer.Purchase a box copy of Win11 from an authorized retailer.Buy a new or refurbished device running Win 11.Situations Need CD Key to Activate Windows 11 Purchase genuine Win11 from Microsoft Store.Upgrade to the newest Windows 11 Insider Preview build on an eligible device running an activated earlier version of Win11 or Windows 11 Preview.Buy a Windows 11 Pro upgrade from the Microsoft Store and successfully activated Windows 11.Upgrade to Windows 11 for free from an eligible device running a genuine Windows 10, 8.1, or 7.Situations Need Digital License to Activate Windows 11 The latter is in form of xxxxx-xxxxx-xxxxx-xxxxx-xxxxx. The former is a method of activation in Win11 that does not require you to enter a product key. Relying on how you got your Windows 11, you will need either a digital license (also called a digital entitlement in Windows 11) or a 25-character Windows CD key to activate it. Once confirm that you are an administrator and using your Microsoft account, go to the Activation page in Settings, choose Add an account, enter your Microsoft account and password, and click Sign in.Īfter that, your activation status will change to Windows is activated with a digital license linked to your Microsoft account.Then, you need to create a Microsoft account. If not, it means that you are logged in with a local account. Confirm that the administrator account is also your Microsoft account by checking to see if an email address is listed above Administrator.If you are not an administrator, just create a local user or administrator account. To confirm you are using an administrator account, navigate to Start > Settings > Accounts > Your info, under your name, you will see Administrator. Sign in as an administrator to add your Microsoft account.Just follow the below steps to achieve that. If you are of the first or second status, you can further link your Microsoft account to your Windows 11 license on your device, which allows you to reactivate Windows using the Activation troubleshooter whenever you make a significant hardware change. Windows is activated using your organization’s activation service.
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MedicateOH: Do you offer curbside delivery? Why or why not? We are also limiting the number of patients that can be in our waiting and dispensing areas. We are continuously cleaning and sanitizing our workplace throughout the day and at the close of business or between shifts.We conduct daily health assessments to our staff to make sure they are fit to work.Face coverings are required for employees and strongly recommended for our patients.JP: Our patients and staff’s health is our utmost priority, to protect everyone from COVID-19 we have established the following protocols: MedicateOH:What changes has the dispensary made to protect patients from COVID-19? JP: We have a comfy waiting room with ample space for patients to feel comfortable as they wait to see one of our patient specialists. MedicateOH: Where do patients stand/sit while they are awaiting their turn? JP: Our mission is to provide a better quality of life with cannabis, now and for future generations. Honestly we couldn’t have asked for better locations or patients and we’ve been too busy to think of additional locations right now, we are just staying present and making sure each of our current patients are being taken care of. Jose Patino, Head of Marketing, Bloom Medicinals: We currently have five wonderful locations rooted in Akron, Columbus, Maumee, Painesville Township and Seven Mile. MedicateOH: How many locations are in Ohio? Are there plans for more locations? The interview has been lightly edited for length and clarity. I recently caught up with Bloom’s Ohio management team to shed some light on the chain’s local operations that serve five cities, the dispensaries’ patient relationships, as well as plans for the future as Ohio enters its third year of its medical marijuana program. About a year ago, I had the pleasure of interviewing CEO Nicole Van Rensburg to learn more about her company’s dispensary chain, Bloom Medicinals, headquartered in south Florida in the city of Boca Raton. Now that you know how to do that, here are some pre-made printable stickers I’m sure you’ll love:
He will point the player towards the Ruined Battlefield and a house where he saw several fresh blooms.Īt this point, Halsin joins the party as a full companion. While it may seem like a 'needle in a haystack' situation at first, Halsin says that the curse cannot completely suppress Thaniel's power, and that the player should look for signs of life in the darkness such as wildflowers where everything else has died. If it can be found, however, it can be reunited with Thaniel, allowing the land to finally heal. He explains that something is wrong and that it seems a part of Thaniel is missing, and asks the party to meet him back at camp to discuss what to do next.Īt camp, Halsin reveals that Thaniel's spirit was split in two when the curse took hold - half was taken to the Shadowfell, but half of him was left behind amidst the curse, and while that half may have been strong enough to resist, it has surely succumbed to the curse over the past hundred years. If Halsin succeeds, he exits the portal with Thaniel in his arms, unconscious.
One such feature enables the player to designate parts of their city as districts. The player proceeds to add roads and residential, industrial and commercial zones, and basic services like power, water and sewage, to encourage residents to move in and supply them with jobs.Īs the city grows beyond certain population tiers, the player unlocks new city improvements, including schools, fire stations, police stations, health care facilities and waste management systems, tax and government edicts, mass transit systems, and other features for managing the city. The player starts with a plot of land – equivalent to a 2-by-2-kilometre (1.2 mi × 1.2 mi) area – along with an interchange exit from a nearby highway, access to a body of water, as well as a starting amount of in-game money. Gameplay Cities: Skylines allows for construction of cities, buildings, and a variety of transportation options. A sequel, Cities: Skylines II, was released on 24 October 2023. The game received favourable reviews from critics, and was a commercial success, with more than twelve million copies sold on all platforms as of June 2022. A remastered edition, also by Tantalus, was released for the PlayStation 5 and Xbox Series X/S in February 2023. Console ports by Tantalus Media were released for the Xbox One and PlayStation 4 game consoles in 2017, for the Nintendo Switch in September 2018, and for Google Stadia in May 2022. The game was first released for the Linux, OS X, and Windows operating systems in March 2015. The game also has built-in support for user-generated content. Since the game's release, various expansions and other DLC have been released for the game. This includes realistic traffic congestion, and the effects of congestion on city services and districts. Colossal's goal was to create a game engine capable of simulating the daily routines of nearly a million unique citizens, while presenting this to the player in a simple way, allowing the player to easily understand various problems in their city's design. However, they reconsidered after the critical failure of the 2013 SimCity game, which provided an opportunity for Paradox to establish a competing franchise. While Colossal felt they had the technical expertise to expand the Cities gameplay into a more full-featured city simulation game, their publisher Paradox Interactive initially held off on the idea, fearing the market dominance of the SimCity series. It is also possible to maintain a city in a sandbox mode, which provides more creative freedom for the player.Ĭities: Skylines is a progression of development from Colossal Order's previous Cities in Motion titles, which focused on designing effective transportation systems. They also work to manage various elements of the city, including its budget, health, employment, traffic, and pollution levels. Players engage in urban planning by controlling zoning, road placement, taxation, public services, and public transportation of an area. The game is a single-player open-ended city-building simulation. City-building, construction and management simulationĬities: Skylines is a 2015 city-building game developed by Colossal Order and published by Paradox Interactive.
Jojo also created dolls that were displayed at their gallery at the Flatiron Building in Wicker Park, and later at a gallery on Chicago Avenue in Ukrainian Village, the Windy City Times reported. They became a mainstay at an assortment of nightclub events– including the Boom Boom Room at Red Dog in Wicker Park and later Green Dolphin Street on Ashland Avenue, and more recently including the Debonair Social Club – also in Wicker Park – and the "Queen!" LGBTQ+ party at Smartbar in Wrigleyville, the Windy City Times noted. The Windy City Times noted that Jojo Baby the performer came into being at the old River North nightclub Shelter. At Kaboom in the West Loop, the Reader reported, they were advised by a bartender to capitalize on their resemblance to the actor and drag performer Divine. The Chicago Reader reported in a 2010 profile that Jojo – looking older than their age – enrolled in beauty school while visiting house music clubs. Their mother, a onetime Chicago Playboy Club bunny, coined the pet name Jojo Baby – which became their stage name and eventually their legal name, according to numerous published reports. Jojo was born Joseph Arguellas, and grew up in the Logan Square neighborhood. Jojo Baby – an artist, drag performer, hairdresser, and fixture in Chicago's nightlife scene – died March 14, following a battle with cancer. Here is a detailed look at 53 notable Chicagoans who passed away this year. But everyone we're honoring here left a mark that helped make Chicago the vibrant, wonderful city we know and love. Some are household names, while you may not be familiar with others. Some of the people you'll read about here spent only a few important years in Chicago, while others lived in Chicago their whole lives long. CHICAGO (CBS/AP) - The people in this list excelled in a variety of industries and talents – sports, the arts, politics, business, print and broadcast journalism, education, activism, public service. *Update* People definitely are drinking her bathwater. Others got straight to the point and spoke the truth about what's going to happen with all the bathwater. This girl out here making money moves.- Lady Pelvic July 2, 2019 I don't know how I feel about this.- RoJayJo July 2, 2019 Belle Delphine made her return to social media and Twitter is rolling in comments about 'Gamer Girl Bathwater. On one hand, it's bringing a meme into fruition, on the other hand, there is most definitely a market. She's making a whole living off of scamming horny people, it's kind of beautiful.- India Hendrie (they) July 2, 2019 Delphine, 19, who has a global following (4.2 million on. That's ridiculous but she has an army of very thirsty losers at her feet and I'm glad she's swindling a fuckton of money from them.- Joe le Clodo July 2, 2019 Belle Delphine, the social media star and so-called gamer girl, made headlines this week for selling her used bath water online. Charlie Nash Instagram model Belle Delphine made waves in the news this month after she decided to sell tubs of her own bath water for 30 a pop. Lots of people called her a genius for being able to make money off this. Worth it! /0Wx51xa4lR- KitCat July 2, 2019 Gonna order enough of those for me to bathe in- Apparition Rey Aureo July 2, 2019 Now, seven months later, she has returned to social media with a new Instagram, TikTok and a bizarre tweet about injuring herself by trying to jump off a roof into a paddling pool and announcing she has uploaded a two minute "rap video" to her YouTube channel.Some people were grossed out, some people thought it was hilarious, and others couldn't believe this was actually real.īeing a girl in 2019 is just playing in easy mode fr- J.™ July 2, 2019 Delphine, 19, who has a global following (4. YouTuber Belle Delphine went viral last year for selling her own bath water before vanishing from social media, but she has returned this week after 7 months. Then Delphine suddenly deleted her Instagram and disappeared from social media, giving no explanation. She made headlines last year after posting on her Instagram (then 4.2m followers strong) announcing she was selling $30 bottles of "bath water for all you thirsty gamer boys." The bath water sold out immediately despite, quite a lot of jokes being made about it online. Last year Belle Delphine, the 21-year-old internet-famous model, noticed that men were jokingly remarking on her photos saying they would drink her bath water. Well now, Belle Delphine has returned after her seven month hiatus with a very bizarre "rap video" and an odd story about how an injury delayed her return to social media. You may remember a very strange story from last year about a YouTuber who began selling her bathwater for $30 a pop, before mysteriously disappearing from all social media without explanation. Similar content being viewed by othersĪdenosine deaminase-deficient severe combined immunodeficiency (ADA-SCID) is a primary immunodeficiency characterized by severe pan-lymphopenia (T −, B − and NK −), severe and recurrent infections, failure to thrive and death in the first year of life, if left untreated 1, 2. Our studies demonstrate at a detailed level that exogenous once-a-week enzyme replacement does not fully correct intra-thymic metabolic or immunological abnormalities associated with ADA deficiency. We also show that thymocyte development in ADA-deficient thymi is arrested at the DN3-to-DN4 stage transition with thymocytes undergoing dATP-induced apoptosis rather than defective TCRβ rearrangement or β-selection. This was associated with lack of effective adenosine (Ado) detoxification in the thymus. Here, we show reduced thymus cellularity in ADA-SCID mice despite weekly PEG-ADA treatment. However, in many patients treated with PEG-ADA, there is suboptimal immune recovery with low T and B cell numbers. Administration of ERT in the form of pegylated bovine ADA (PEG-ADA) has proved a life-saving though non-curative treatment for ADA-SCID patients. While untreated ADA-SCID is a fatal disorder, there are different therapeutic options available to restore ADA activity and reconstitute a functioning immune system, including enzyme replacement therapy (ERT). Lack of ADA results in the intracellular accumulation of toxic metabolites which have effects on T cell development and function. Deficiency of adenosine deaminase (ADA, EC3.5.4.4), a housekeeping enzyme intrinsic to the purine salvage pathway, leads to severe combined immunodeficiency (SCID) both in humans and mice. |
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